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Schizophrenia is a severe mental disorder with a profound impact on patients, their families, caregivers and society. The global prevalence of lifetime schizophrenia is...

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Schizophrenia is one of the most debilitating severe mental illnesses with significant impact,1 irrespective of culture or socioeconomic class.2 Over the decades, antipsychotic medication...

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Schizophrenia is the most severe of all mental disorders and affects about 1% of the population. The main disturbances of schizophrenia comprise positive symptoms,...

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Animals have long served as experimental models for studying human biology and diseases. With the biomolecular revolution in the past three decades, genetically manipulated...

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From a historical perspective, the first experimental pancreatitis was induced by Claude Bernard in 1856 by the injection of bile and olive oil into...

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The management of mental health disorders within a nation requires a system of care extending from the primary health care setting to tertiary and...

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Myopia affects up to 70% of adults in Singapore, Taiwan, Hong Kong and Japan. The prevalence rates in these Asian countries are higher than...

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Schizophrenia – a mind torn asunder – is a difficult illness to live with, both for the patient as well as for the caregiver;...

Clinical and Social Correlates of Duration of Untreated Psychosis in First-episode Psychosis Patients

First-episode studies of schizophrenia have reported that the longer the duration of untreated psychosis (DUP), the poorer the response to antipsychotic medication and treatment...

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It is well known that serious and persistent mental illness can result in diminished ability to function effectively in many life domains, such as...

Assertive Community Treatment (ACT) in Singapore: A 1-year Follow-up Study

Major mental illnesses can be persistent and debilitating, significantly impairing patients’ social, occupational and daily functions. The Global Burden of Disease lists schizophrenia among...

Preventive Psychiatry

In medicine, measures that save the most lives and improved the quality of life of millions have largely been public health measures that in...

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Schizophrenia is a serious psychotic condition characterised by delusions, hallucinations and disordered behaviour. The Global Burden of Disease lists schizophrenia among the top 10...

Measuring Memory-Prediction Errors and their Consequences in Youth at Risk for Schizophrenia

Despite the common experience of the world as mostly stable and meaningful, the human nervous system continuously engages with a vast array of ambiguous...

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Hallucinations are a hallmark symptom of schizophrenia and are commonly observed in other psychotic disorders. Auditory hallucinations (AH) are the most common subtype ...

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