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Topoisomerase-I Inhibitors in Gynaecologic Tumours

Topoisomerases are essential nuclear enzymes with a multiplicity of cellular functions involving DNA replication, RNA transcription, mitosis, and chromosome condensation. Two classes have been...

Laparoscopic Totally Extraperitoneal Inguinal Hernioplasty: An Audit of the Early Postoperative Results of 100 Consecutive Repairs

Inguinal hernia is one of the commonest surgical pathologies in the world. Laparoscopic totally extraperitoneal repair has been gaining popularity in recent years. This article...

Remifentanil in the Management of Laparoscopic Resection of Phaeochromocytoma – Case Reports

The perioperative management of surgery for laparoscopic resection of phaeochromocytoma presents a significant challenge. Many different anaesthetic techniques and drugs have been used to...

Investigating the Infertile Couple

Infertility is defined as the inability to conceive after 1 to 2 years of unprotected intercourse. In general, an estimated 84% of all women...

Hand-assisted Laparoscopic Living Donor Nephrectomy

Minimally invasive donor nephrectomy using laparoscopic techniques has become a very attractive method of procuring kidneys from live donors, compared to the traditional standard...

Laparoscopic Appendicectomy in Children: A Trainee’s Perspective

The advent of laparoendoscopic surgery in children has opened new avenues of treatment with added benefits but at the same time demands adequate training...

Laparoscopic-assisted Colon and Rectal Surgery – Lessons Learnt from Early Experience

Great strides in laparoscopic surgical techniques have been progressively made throughout the various surgical subspecialties. More procedures can be performed laparoscopically today than when...

Laparoscopic Partial Nephrectomy for Renal Tumours: Early Experience in Singapore General Hospital

With the increasing availability of ultrasound and computed tomography scans, more patients are being diagnosed with incidental renal tumours. Up to 80% of tumours...

Laparoscopic Pelvic Surgery for Endometrial Cancer

The traditional approach for the treatment of endometrial cancer by laparotomy is increasingly being replaced by laparoscopic surgery.1 Like laparotomy, operative laparoscopy can accomplish...

Development of Bariatric Surgery: The Effectiveness of a Multi-disciplinary Weight Management Programme in Hong Kong

Obesity is one of the most common chronic illnesses in the Western World with a frequency of 10% to 15%. It causes or exacerbates...

Laparoscopic Common Bile Duct Exploration: Our First 50 Cases

Since its introduction a few decades ago, endoscopic retrograde cholangiopancreatography (ERCP) has brought about a significant change in the management of choledocholithiasis. With continual...

The Contribution of Rapid Intraoperative Cytology in the Evaluation of Endometrial Cancer Spread

Tumour staging is of great importance to the treatment of patients with oncological diseases. The therapeutic approach of the patient largely depends on the...

Evolution and trends in the adoption of laparoscopic liver resection in Singapore: Analysis of 300 cases

Over the past few decades, the introduction of laparoscopic surgery has been the biggest game changer in abdominal surgery.1 However, although the first laparoscopic...

Laparoscopic liver resection: Global diffusion and learning curve

Laparoscopic liver resection (LLR) is being utilised with increasing frequency worldwide, as initial concerns about the safety and feasibility of LLR, such as the...