Schizophrenia is one of the most debilitating severe mental illnesses with significant impact,1 irrespective of culture or socioeconomic class.2 Over the decades, antipsychotic medication has been the mainstay of treatment for patients with schizophrenia. Nevertheless, about 25% of patients do not respond to first-line antipsychotic medication, with more than...

In 1967, Shealy1first introduced dorsal column stimulator for patients suffering from terminal cancer pain based on the gate control theory of pain proposed by Melzack and Wall.2 In the first decade after its introduction, the success of follow-up rate was poor, and the spinal cord stimulation (SCS) soon fell...

The past half-century has seen a revolution in how we approach pain with the rethinking of the organisation of pain management. This began when John Bonica recognised the fragmentation of care that existed for many pain sufferers.1 He initiated the first interdisciplinary clinic for the assessment and treatment of...