The last decade has seen a progressive change in the style of management of severe acute renal failure (acute renal failure which requires the...

The relationship between lipid disorders and arthritis is manifold. Hyperlipidaemia may manifest clinically in the musculoskeletal system. In 1968, Khachadurian studied 14 families of...

Despite intensive research and intervention, trauma continues to be the leading cause of death during the first three decades of life in the USA,...

Synder in 1932 wrote the first report on the Mendelian inheritance of the inability to taste phenylthiourea. Twenty-five years later, Arno Motulsky suggested hereditary...

CYP2D6 is a cytochrome P450 isoenzyme that plays a role in the metabolism of a wide range of drugs, particularly cardiovascular and psychotropic agents....

Minimal change nephrotic syndrome (MCNS) is the most common cause of childhood nephrotic syndrome. It is characterised by the presence of gross proteinuria, hypoalbuminaemia,...

Autoimmune processes have been implicated in the pathogenesis of schizophrenia. Several pieces of indirect evidence point towards a role of autoimmune processes in at...

During intense exercise, immune disturbances can occur through an increase in plasma pro- and anti-inflammatory cytokines and lipopolysaccharide (LPS) concentrations, and post-exercise leukocytosis and...

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterised by severe joint deformities due to bony erosions and tendon damage. The chronic inflammatory process...