Original Article
Is EQ-5D a Valid Quality of Life Instrument in Patients With Parkinson’s Disease? A Study in Singapore
The EQ-5D is a preference-based, generic instrument that measures quality of life in three different ways.1 The first part is a descriptive system providing...
Original Article
Prevalence and Impact of Mental and Physical Comorbidity in the Adult Singapore Population
The co-occurrence of mental and medical disorders in the same person, regardless of the chronological order in which they occurred or their causal relationship—commonly...
Others
2013 Runme Shaw Memorial Lecture: Clinical Applications of Stem Cells in Modern Medicine—21st Century and Beyond
The rapid advancement of biomedical research in the recent years was propelled by a series of groundbreaking technological inventions and breakthrough discoveries. In this...
Images in Medicine
Blue Dye, Blue Skin
A 59-year-old Chinese lady was scheduled for wide excision of an invasive ductal carcinoma of the left breast, with sentinel lymph node biopsy (SLNB)....
Letter to the Editor
Role of Multi-Detector Computed Tomography (MDCT) in Diagnosis of Pulmonary Artery Dissection: A Rare but Fatal Entity
A 33-year-old male who was undergoing treatment with phosphodiesterase 5 inhibitor and anticoagulant for idiopathic pulmonary arterial hypertension presented to the emergency department with...
Letter to the Editor
Topical Papaverine as Rescue Therapy for Vasospasm Complicated by Unsecured Aneurysm
A 55-year-old female presented in 2010 with a World Federation of Neurosurgeons (WFNS) grade 3 subarachnoid haemorrhage (SAH). She had aneurysms of the right...
Letter to the Editor
A 58-year-old Woman with Dry Cough and Pulmonary Nodules
Pulmonary epithelioid haemangioendothelioma is a rare vascular neoplasm of endothelial origin. We describe a case which involved solely the lungs and a novel therapeutic...
Commentary
Early Influences in Childhood Obesity—Implications for Adult Metabolic Disease
In the past 20 years, an epidemic of adult and childhood obesity has swept through the developed world resulting in the “globesity” epidemic. This...
Commentary
Projecting the Number of Older Singaporeans with Activity of Daily Living Limitations Requiring Human Assistance Through 2030
Similar to other developed countries in Asia, including Japan, South Korea and Taiwan, the population of Singapore is ageing rapidly. In 2011, 9.3% of...
Review Article
Changing Landscape of Nursing Homes in Singapore: Challenges in the 21st Century
Nursing homes trace their evolution to American alms-houses in the 1930s where retired nurses welcomed the elderly and ill into their homes. In Singapore,...
Original Article
Percutaneous Transluminal Angioplasty of Transplant Renal Artery Stenosis
Renal transplantation has become a successful means of treatment for patients with end-stage renal failure. However, in patients with kidney transplants, graft dysfunction can...
Original Article
Effect of Using an Audiovisual CPR Feedback Device on Chest Compression Rate and Depth
There is increasing evidence to show that good quality cardiopulmonary resuscitation (CPR) is important in achieving better resuscitative outcomes. One of the determinants for...
Original Article
Surgical Outcome in Thoracolumbar Fractures Managed by Short-segment Pedicle Instrumentation
Thoracolumbar junction vertebrae are particularly vulnerable in traumatic injuries and up to 90% of all spinal fractures occur in this area. Treatment of thoracolumbar...
Original Article
Wake-up Stroke and Onset-to-door Duration Delays: Potential Future Indications for Reperfusion Therapy
In ischaemic stroke, acute reperfusion therapy aims to recanalise arterial obstruction leading to salvage of hypoperfused cerebral tissue with the goal of improving clinical...
Original Article
Determinants of Health-Related Quality of Life Among Community Dwelling Elderly
Singapore is experiencing an unprecedented age shift as the post-war baby boomers turn 65 years in 2012. Currently there are 378,700 people aged 65...
Editorial
Improving the End-of-Life Experience in Singapore: Building Capacity in Palliative Care Education and Research
Singapore is ageing rapidly. Whereas ageing symbolises advancements that the country has made in public health and medicine over the past few decades, it...
Original Article
Assessing the Content Validity of the EQ-5D Questionnaire Among Asians in Singapore: A Qualitative Study
EQ-5D is a tool to measure and value health status. It is a standardised questionnaire that comprises 2 components: a Descriptive System (DS) on...