Original Article
Burden of antibiotic resistance in infections among very-low-birthweight infants in Singapore
Recent reports have described an increased predominance of Gram-negative organisms (Escherichia coli, Klebsiella species ) among invasive bacterial infections in early- and late-onset neonatal sepsis in many settings.1-5 This changing pattern of infections is particularly concerning due to the global spread of drug resistance among Gram-negatives, leading to increasingly...
Editorial
Pharmacokinetic and pharmacogenomic considerations in managing use of nirmatrelvir-ritonavir and molnupiravir and dermatological treatments
The COVID-19 pandemic has been unprecedented in its impact on global health, economic, financial, psychosocial and political systems. The World Health Organization estimates approximately 627 million confirmed cases and 6.5 million deaths reported globally.1 In Singapore, the swift and prompt public health response of the government during the early...
Others
Clinical Drug Development—Practical Issues in Clinical Pharmacology Studies
Clinical pharmacology (CP) as a discipline comes in many guises. The perception for a medical student, and for many doctors, may be that of a painful series of lists of drugs to learn, the drugs being traditionally classified by functionality and effects.
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