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The efficacy and safety of radiofrequency ablation in papillary thyroid carcinoma: A systematic review and meta-analysis

Malignant nodules account for 5–15% of all thyroid nodules and papillary thyroid carcinoma (PTC) accounts for 85% of that.10 Most guidelines recommend surgery as the first-line treatment for PTC.11 However, surgery does carry a risk for complications, such as hypothyroidism and recurrent laryngeal nerve damage leading to voice hoarseness.12-17...

Ablation therapies for paroxysmal atrial fibrillation: A systematic review and patient-level network meta-analysis

Atrial fibrillation (AF) is a pertinent health condition that is seeing a sustained rise in global incidence and prevalence.1 In particular, paroxysmal AF (PAF), despite its transient nature, is associated with a slow but steady progression to persistent AF2 and increased mortality compared to patients without AF.3 Furthermore, patients...

Development of the Human Intrahepatic Biliary System

The development of the human biliary system has been studied extensively. This knowledge is essential to the understanding of the pathogenesis of a spectrum of diseases termed “ductal plate malformation” (DPM). This article is available only as a PDF. Please click on “Download PDF” on top to view the full...

Paediatric living-donor liver and kidney transplantation during COVID-19

Dear Editor, The coronavirus disease 2019 (COVID-19) pandemic has impacted global healthcare including paediatric solid organ transplantation (SOT). We report our experience of resuming paediatric living-donor SOT during COVID-19, which took into account safety considerations for living donors, paediatric recipients and the transplant healthcare team. The US Centers for Disease...

Two Case Reports on Incessant Left Ventricular Tachycardia: Curative Therapy with Radiofrequency Ablation

Left ventricular tachycardia is a recognisable condition in patients with otherwise structurally normal heart. It may arise from various foci in the left ventricle. This article is available only as a PDF. Please click on “Download PDF” on top to view the full article.

Image-guided Radiofrequency Ablation of Liver Malignancies: Experience at Singapore General Hospital

Radiofrequency (RF) ablation for the treatment of focal liver malignancies is a relatively new image-guided procedure that is gaining increasing acceptance in the radiologic and surgical community, particularly as an alternative treatment option for patients who have inoperable tumours. The potential benefits of minimally invasive image-guided ablation, as compared...

Liver Transplantation in Asia: Past, Present and Future

Liver transplantation is the best treatment modality for patients with end-stage liver diseases. It has been landmarked as one of the most important advances in the medical field. Its applicability is expanding tremendously worldwide, particularly in many Asian countries. The history of liver transplantation dates back to 1963 when...

Laparoscopic liver resection: Global diffusion and learning curve

Laparoscopic liver resection (LLR) is being utilised with increasing frequency worldwide, as initial concerns about the safety and feasibility of LLR, such as the risk of uncontrolled major haemorrhage and potential compromise of oncologic outcomes, were not supported by the data. On the contrary, LLR was found to be...

Pilot study of single-session radiofrequency ablation of benign thyroid nodules in Singapore

Radiofrequency ablation (RFA) has been shown to be safe and efficacious in the treatment of benign thyroid nodules. Ion agitation during RFA generates high temperatures between 60 and 100 degree Celsius to cause tissue damage and size reduction.   This article is available only as a PDF. Please click on "Download...