Actinomycosis is a chronic granulomatous disease caused by gram-positive, anaerobic Actinomyces bacteria. These commensal microbes can cause opportunistic infection
following mucosal breach. Classically, histology shows granulomatous inflammation with abscesses or sinuses containing sulphur granules, bearing clusters of grampositive, non-acid-fast bacteria with club-shaped ends within dilated infundibulocystic cavities.
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