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Volume 52, Number 4 April 2023

A Singapore study examined the association between domain-specific physical activity (e.g. work, transport and leisure) and sedentary behaviour, with type 2 diabetes mellitus (T2DM) and hypertension.

Higher leisure-related physical activity was associated with lower odds of T2DM and hypertension. Higher sedentary time was associated with higher odds of hypertension. Lifestyle modifications can reduce the risk of T2DM and hypertension.

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Featured

Original Article

Benefits of leisure-related physical activity and association between sedentary time and risk for...

Yen Sin Koh, PV Asharani, Fiona Devi, Kumarasan Roystonn, Peizhi Wang, Edimansyah Abdin, Chee Fang Sum, Eng Sing Lee, Siow Ann Chong, Mythily Subramaniam
Diabetes mellitus and hypertension are serious public health issues. Approximately 451 million individuals worldwide aged 18–99 years were living with diabetes in 2017, and this number is expected to increase to 693 million by 2045.1 More than 90% of...
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Editorial

Promoting physical activity for population health

Aidan Lyanzhiang Tan
The chronic disease burden has risen globally. In Singapore, between 2007 and 2021, the crude prevalence of hyperlipidaemia (8.2–13.9%), hypertension (12.7–15.7%) and diabetes (4.9–6.9%) has increased.1 Based on the Global Burden of Disease Study (2019), lack of physical activity...
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Original Article

Association between body mass index, body image and self-esteem with sexual function: A...

Farah Safdar Husain, Dypti Lulla, Timothy Kai Cheng Tay, Jean-Jasmin ML Lee, Satvinder Singh Dhaliwal, Seng Bin Ang
Satisfaction with sexual activity is a good predictor of global life satisfaction.1 Problems with sexual function can lead to lower partner satisfaction and affect a woman’s mental and physical health.2 The prevalence of sexual dysfunction in premenopausal women globally...
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Editorial

Self-esteem and positive body image to overcome female sexual dysfunction

Ahmet Cihan, Esra Cihan
Human sexuality is arguably one of the main pillars of health, like nutrition and sleep. Improvements in diagnostic and therapeutic biotechnologies have enabled focus on not only deadly diseases, but also on the quality of life and sexual functions...
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Original Article

Transitional care strategies at emergency department for elderly patients: A multicentre study in...

Shariel Leong, Rebecca HS Ong, Melvin Ng, SH Arron Ang, Steven HC Lim
In Singapore, greater efforts are being directed towards developing an integrated health and social ecosystem under the new Healthier SG strategy announced by the Ministry of Health. This life-course approach aims to promote overall healthier living in collaboration with...
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Commentary

Artificial intelligence innovation in healthcare: Relevance of reporting guidelines for clinical translation from...

Zhen Ling Teo, Ann Kwee, John CW Lim, Carolyn SP Lam, Dean Ho, Sebastian Maurer-Stroh, Yi Su, Simon Chesterman, Tsuhan Chen, Chorh Chuan Tan, Tien Yin Wong, Kee Yuan Ngiam, Cher Heng Tan, Danny Soon, May Ling Choong, Raymond Chua, Sutowo Wong, Colin Lim, Wei Yang Cheong, Daniel SW Ting
Artificial intelligence (AI) and digital innovation have revolutionised many sectors and industries, prominently including healthcare during the coronavirus disease 2019 (COVID-19) pandemic.1 For example, deep learning, which is a subset of the state-of-the-art machine learning techniques, has shown robust...
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Letter to the Editor

Real-world challenges when facilitating terminal discharge in Singapore

Poh-Heng Chong, Irene Hii, Zhi-Zheng Yeo
Dear Editor, During the Ministry of Health workplan seminar held on 2 June 2022, Minister Ong Ye Kung expounded the notion of a good death and outlined the Ministry’s vision and strategy for better care (and experience) for all near...
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Letter to the Editor

Suboptimal adherence to medical therapy in patients undergoing lower limb angioplasty in Singapore

Sze Ling Chan, Charyl Jia Qi Yap, Nicholas Graves, Tze Tec Chong, Tjun Yip Tang
Dear Editor, Chronic limb-threatening ischaemia (CLTI) is the advanced stage of peripheral arterial disease (PAD) and patients with this condition face a very high risk of major adverse cardiovascular events and mortality. Several guidelines strongly recommend evidence-based medical therapy (EBMT)...
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Editorial

Challenges with mainstreaming genetic testing for metastatic prostate cancer treatment in Singapore

Jianbang Chiang, Joanne Yuen Yie Ngeow
Compared with other solid tumours, patients with metastatic prostate cancer typically have better survival in the range of years.1 The long survival translates to a high prevalence, and thus, a large number of men living with prostate cancer. Singapore...
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Review Article

An approach to genetic testing in patients with metastatic castration-resistant prostate cancer in...

Ravindran Kanesvaran, Puey Ling Chia, Edmund Chiong, Melvin Lee Kiang Chua, Nye Thane Ngo, Samuel Ow, Hong Gee Sim, Min-Han Tan, Kiang Hiong Tay, Alvin Seng Cheong Wong, Siew Wei Wong, Puay Hoon Tan
Prostate cancer is the fifth most common cancer in Asian men, and with its rising incidence, is emerging as a health priority in Asia.1 Across Asian countries, age-standardised incidence rates (ASIRs) of prostate cancer range from 0.9 to 56.1...
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Editorial

Preventing recurrent hypersensitivity reactions to iodinated contrast media

Wey Chyi Teoh
Iodinated contrast media (ICM) is one of the most commonly used drugs in the practice of modern medicine. ICM, as the name implies, is a contrast media that contains iodine. It is frequently used in computed tomography (CT) and...
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Original Article

Clinical outcomes and management of contrast hypersensitivity in patients requiring repeated computed tomography...

Pearlyn Mei Ping Wong, Si Min Chiow, Chau Hung Lee, Sze-Chin Tan, Martin Weng Chin H’ng
Allergic and non-allergic hypersensitivity reactions to iodinated contrast media (ICM) are increasingly recognised, particularly the latter where there is greater clarity on pathomechanisms.1 There is limited evidence for the use of corticosteroids as premedication to prevent the occurrence of...
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Call For Papers

The Annals is the official journal of the Academy of Medicine, Singapore. Established in 1972, Annals is the leading medical journal in Singapore which aims to publish novel findings from clinical research as well as medical practices that can benefit the medical community.

Published monthly, online, open-access and peer-reviewed, Annals is indexed in Index Medicus, Science Citation Index – Expanded, ISI Alerting Services, and Current Contents/ Clinical Medicine. Impact Factor for the Annals in 2021 is 8.713 and 5-year Impact Factor is 5.544.

The rapidly ageing population and enlarging burden of chronic diseases require a proportionate emphasis on health promotion and disease prevention. A health system that is more data-driven and patient-centric, which leverages the innovative use of technology and digital solutions, will be areas warranting research attention and coverage. The Annals invites submission of manuscripts that advance the scientific basis of clinical knowledge, and the practice of medicine in Singapore and internationally. We welcome submissions that address challenges in the management of chronic diseases (e.g. cancer, cardiovascular diseases, ageing, diabetes mellitus and neurological diseases), and use of technology and digital medicine to improve patient care.

Papers of sufficient merits will be published. Authors will also be notified if their manuscripts are deemed not suitable for publication.

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MOST CITED ARTICLES

Commentary

Mental Health Strategies to Combat the Psychological Impact of Coronavirus Disease...

Cyrus SH Ho, Cornelia YI Chee, Roger CM Ho
Review Article

Review on Epidemic of Obesity

Serena Low, Mien Chew Chin, Mabel Deurenberg-Yap
Review Article

Rationale for Redefining Obesity in Asians

Serena Low, Mien Chew Chin, Stefan Ma, Derrick Heng, Mabel Deurenberg-Yap
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MOST VIEWED ARTICLES

Original Article

Healthcare cost of patients with multiple chronic diseases in Singapore public...

Shu Yun Tan, Kaiwei Jeremy Lew, Ying Xie, Poay Sian Sabrina Lee, Hui Li Koh, Yew Yoong Ding, Eng Sing Lee
Original Article

Safety and side effect profile of Pfizer-BioNTech COVID-19 vaccination among healthcare...

See Ming Lim, Hwang Ching Chan, Amelia Santosa, Swee Chye Quek, Eugene Hern Choon Liu, Jyoti Somani
Original Article

Pericarditis and myocarditis after COVID-19 mRNA vaccination in a nationwide setting

Jonathan Yap, Mun Yee Tham, Jalene Poh, Dorothy Toh, Cheng Leng Chan, Toon Wei Lim, Shir Lynn Lim, Yew Woon Chia, Yean Teng Lim, Jonathan Choo, Zee Pin Ding, Ling Li Foo, Simin Kuo, Yee How Lau, Annie Lee, Khung Keong Yeo
Original Article

Adverse reactions and safety profile of the mRNA COVID-19 vaccines among...

Joshua TC Tan, Clive Tan, Jeremy Teoh, Wahab MT, Guan Zhong Tan, Reon Yew Zhou Chin, Anne Lee, Adeliza Mutalib, Poh Lian Lim
Original Article

Prevalence of burnout among healthcare professionals in Singapore

Kok Hian Tan, Boon Leng Lim, Zann Foo, Joo Ying Tang, Mabel Sim, Phong Teck Lee, Kok Yong Fong
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