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Current Issue

Volume 51, Number 6 June 2022

An observational study conducted in 5 tertiary hospitals in Singapore examined the characteristics, treatment modalities, clinical outcomes and nutrition interventions of critically ill patients with COVID-19 in the intensive care unit.

Inadequate calories and protein, and late enteral nutrition (>36 hours) was associated with higher hospital mortality. Obesity, frequent usage of neuromuscular blockade, prone therapy, and dialysis had considerable implications on nutritional care. More audits may help refine nutritional interventions and guidelines for this evolving disease.

Featured

Nutrition support practices for critically ill patients with severe acute respiratory syndrome coronavirus-2:...

Within 3 weeks of the World Health Organization declaring the COVID-19 pandemic on 11 March 2020, the Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (ASPEN) developed a set of nutrition guidelines that...

Challenges and considerations in delivering nutritional therapy in the ICU during COVID-19 pandemic

Coronavirus disease 2019 (COVID-19) has created unprecedented challenges for healthcare workers in Singapore and across the world. Providing clinical nutrition and metabolic care to patients with COVID-19 has been highly challenging. In this issue of the Annals, Lew et...

Inter-hospital trends of post-resuscitation interventions and outcomes of out-of-hospital cardiac arrest in Singapore

Out-of-hospital cardiac arrest (OHCA) have notoriously been a medical issue with high morbidity and mortality.1 It is a multifaceted problem with a multitude of aetiologies,2 and as such various factors influence the outcome of OHCA patients. The management of OHCA...

Out-of-hospital cardiac arrest in Singapore: Can we do better?

Cardiac arrests are unpredictable events that frequently result in death or significant residual morbidity among survivors. These sudden events affect not only the individual, but are understandably also significant life events and stressors for the family and friends. As...

Congenital cytomegalovirus infection: Advocating for screening and education

Cytomegalovirus (CMV) infection is the leading non-genetic cause of congenital neurosensory hearing loss in children, accounting for 21% of cases of hearing loss at birth and 25% of deafness at age 4 years.1 It can also give rise to...

Functional improvement after inpatient rehabilitation in community hospitals following acute hospital care

Early inpatient rehabilitation therapy has been known to have beneficial impact on physical function and mobility, psychological status and cognitive function of patients following an acute medical event requiring hospitalisation.1 Following an acute hospital care, those who have been...

Epidemiological trends and outcomes of children with aural foreign bodies in Singapore

Aural foreign bodies (FBs) commonly present to the emergency department (ED) worldwide. Children represent the majority of the population, believed to be due to their inquisitive minds and experimental nature.1 Aetiologies for aural FBs include accidental or intentional insertion...

Sepsis, cardiovascular events and short-term mortality risk in critically ill patients

Sepsis is defined as “life-threatening organ dysfunction caused by a dysregulated host immune response to infection”.1 It is one of the most common conditions afflicting intensive care unit (ICU) patients, causing a high mortality rate. An estimated 48.9 million...

Prevalence, risk factors and parental perceptions of gastroesophageal reflux disease in Asian infants...

Functional gastrointestinal (GI) disorders, such as colic, gastroesophageal reflux (GER) and constipation, are common in infants under 1 year. They are a frequent cause of concern for parents and result in a significant healthcare burden1,2 due to their negative...

The Lancet Commission on diagnostics: What it means for Singapore

Effective healthcare systems depend on a functioning healthcare value chain—defined as a care cascade comprising screening, diagnosis, treatment and follow-up. The tremendous heterogeneity and global disparity regarding this healthcare value chain has been one of the fundamental problems with...

Consensus statement on Singapore integrated 24-hour activity guide for children and adolescents

The World Health Organization’s Global action plan for the prevention and control of noncommunicable diseases 2013–2020 provided guiding principles for national efforts in controlling and reducing non-communicable diseases (NCDs).1 The major NCDs include cardiovascular diseases, cancers, chronic respiratory diseases,...

Prevalence and correlates of psychological distress and coronavirus anxiety among hospital essential services...

The Coronavirus Disease 2019 (COVID-19) has affected almost all geographies in the world since 2020. Many countries have imposed strict isolation measures to contain the spread of this disease. While the majority of the population has been working from...

Call For Papers


The Annals is the official journal of the Academy of Medicine, Singapore. Established in 1972, Annals is the leading medical journal in Singapore which aims to publish novel findings from clinical research as well as medical practices that can benefit the medical community.

Published monthly, online, open-access and peer-reviewed, Annals is indexed in Index Medicus, Science Citation Index – Expanded, ISI Alerting Services, and Current Contents/ Clinical Medicine. Impact Factor for the Annals in 2021 is 8.713 and 5-year Impact Factor is 5.544.

The rapidly ageing population and enlarging burden of chronic diseases require a proportionate emphasis on health promotion and disease prevention. A health system that is more data-driven and patient-centric, which leverages the innovative use of technology and digital solutions, will be areas warranting research attention and coverage. The Annals invites submission of manuscripts that advance the scientific basis of clinical knowledge, and the practice of medicine in Singapore and internationally. We welcome submissions that address challenges in the management of chronic diseases (e.g. cancer, cardiovascular diseases, ageing, diabetes mellitus and neurological diseases), and use of technology and digital medicine to improve patient care.

Papers of sufficient merits will be published. Authors will also be notified if their manuscripts are deemed not suitable for publication.

MOST CITED ARTICLES

Review on Epidemic of Obesity

Rationale for Redefining Obesity in Asians

MOST VIEWED ARTICLES

Healthcare cost of patients with multiple chronic diseases in Singapore public...

Safety and side effect profile of Pfizer-BioNTech COVID-19 vaccination among healthcare...

Adverse reactions and safety profile of the mRNA COVID-19 vaccines among...