Current Issue

Volume 53, Number 12 December 2024

An intervention team comprising specialist clinicians, hospital administrators and quality improvement staff examined the outcomes of care pathway for emergency laparotomy patients.

Featured

Perioperative emergency laparotomy pathway for patients undergoing emergency laparotomy: A propensity score matched study

Patients requiring emergency laparotomy (EL) are a vulnerable subset within general surgery, with reported 30-day mortality rates ranging from 9% to 18%, which is 3 times higher than similar elective operations.1-3 Unlike elective surgeries, the care for EL patients...

Intrapleural fibrinolytic therapy for pleural infections: Outcomes from a cohort study

Pleural infection, defined as bacterial infection and replication in the pleural space,1 remains a significant cause of mortality.2 Over 80,000 cases of pleural infection are diagnosed each year in the US and the UK.3,4 Data from East Asia suggest...

Pharmacogenomics in psychiatry: Practice recommendations from an Asian perspective (2024)

Pharmacogenomic testing in psychiatry is an emerging area with the potential clinical application of guiding medication choice and dosing. Interest in this area has been fanned by commercial pharmacogenomic providers, who have commonly marketed multiple-gene or combinatorial panels that...

Optimising dementia screening in community-dwelling older adults: A rapid review of brief diagnostic tools in Singapore

Persons living with dementia experience chronic and progressive cognitive decline in 1 or more cognitive domains, affecting their everyday activities.1 Globally, the number of persons living with dementia is expected to rise from 55 million in 2019 to 139...

Gender dysphoria in children and adolescents: A retrospective analysis of cases in Singapore

The understanding of gender dysphoria (GD) has evolved significantly, from early conflations of sexual orientation and gender identity to its recognition as a distinct condition characterised by gender incongruence. GD is now classified in the Diagnostic and Statistical Manual...

Unplanned hospitalisations among subsidised nursing home residents in Singapore: Insights from a data linkage study

Hospitalisations pose hazards and safety risks to nursing home (NH) residents who may be frail, cognitively impaired, suffering from multi-morbidities and physically dependent,1 with propensity to develop adverse outcomes such as functional, psychological or cognitive decline, iatrogenic complications, and...

Updated consensus guidelines for management of moderate-to-severe atopic dermatitis in Singapore: Integrating biologics, Janus kinase inhibitors and conventional therapies

Atopic dermatitis (AD) is a chronic inflammatory skin disease characterised by dry skin, localised red scaly patches, intense itching and skin pain.1-4 Although its onset most commonly occurs before the age of 5, AD can develop during later childhood,...

Corticosteroids in critically ill patients with community-acquired pneumonia: A systematic review and Bayesian meta-analysis

Community-acquired pneumonia (CAP) is a common cause of hospital mortality. Each year, in the US alone, more than 1.5 million pneumonia patients are hospitalised, and 1 in 3 of them die within 1 year.1 Mortality is the highest among...

Five-year outcomes of a holistic programme for managing early chronic kidney disease in primary care

Singapore has the third highest incidence and sixth highest prevalence of end-stage kidney disease (ESKD) in the world.1 Globally, chronic kidney disease (CKD) is estimated to affect over 850 million people, with a prevalence of 13.4% among adults worldwide.2...

Factors influencing smoking cessation: Insights from Singapore’s nationwide health and lifestyle survey

The global prevalence of smoking has declined over the years. According to authors utilising data from the Global Burden of Disease, Injuries, and Risk Factors Study, from 1990 to 2020, the number of male smokers fell by 27.2%, whereas...

Enhancing guidelines for managing cognitively impaired drivers: Insights from Western evidence for Asian adaptation

Licensing authorities rely on medical certifications of fitness-to-drive when renewing licence for drivers who are at higher risk of crashes. Drivers with cognitive impairment are 2 to 8 times more likely to be involved in a crash compared to...

Mental wellness and health-related quality of life of young adult survivors of childhood cancer in Singapore

Advancements in technology and cancer treatments have improved childhood cancer survival rates, with up to 85% surviving 5 years or more.1 The Malaysia-Singapore Leukaemia Study Group reported an improvement in overall 5-year survival for the past 20 years in...

Call For Papers


The Annals is the official journal of the Academy of Medicine, Singapore. Established in 1972, Annals is the leading medical journal in Singapore which aims to publish novel findings from clinical research as well as medical practices that can benefit the medical community.

Published monthly online, the Annals is indexed in PubMed/MEDLINE, Science Citation Index Expanded, Current Contents/Clinical Medicine and SCOPUS. We are ranked in the first quartile in the competitive category of Medicine (General and Internal) (Clarivate 2023).

The rapidly ageing population and enlarging burden of chronic diseases require a proportionate emphasis on health promotion and disease prevention. A health system that is more data-driven and patient-centric, which leverages the innovative use of technology and digital solutions, will be areas warranting research attention and coverage. The Annals invites submission of manuscripts that advance the scientific basis of clinical knowledge, and the practice of medicine in Singapore and internationally. We welcome submissions that address challenges in the management of chronic diseases (e.g. cancer, cardiovascular diseases, ageing, diabetes mellitus and neurological diseases), and use of technology and digital medicine to improve patient care.

Papers of sufficient merits will be published. Authors will also be notified if their manuscripts are deemed not suitable for publication.

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