Volume 55, Number 10 October 2026
Over an 8-year period, personal stigma towards schizophrenia decreased. Continued targeted education can help further strengthen public recognition of the condition.
Illustration by Maria De-Castro
Featured
Review Article
Efficacy of AI in the diagnosis of oral squamous cell carcinoma from clinical images: A systematic review and meta-analysis
Oral squamous cell carcinoma (OSCC) is the most prevalent and life-threatening malignancy of the oral cavity, representing approximately 90% of all oral malignancies.1 Lip and oral cavity cancers accounted for an estimated 452,205 new cases and 194,108 deaths worldwide...
Commentary
Lessons learned from real-world implementation of entrustable professional activities in an internal medicine residency programme
In the early 2000s, the competency-based medical education (CBME) framework became the gold standard for clinical training and assessment of physicians in postgraduate subspecialty programmes. These physicians were regularly assessed on Accreditation Council for Graduate Medical Education (ACGME) core...
Commentary
Case studies and expert opinion on the management of complement-mediated and secondary thrombotic microangiopathy in Singapore
Complement-mediated thrombotic microangiopathy (C-TMA)—also known as atypical haemolytic uraemic syndrome1—refers to the primary form of the syndrome, which arises from genetic abnormalities that result in uncontrolled complement pathway activation.2,3 C-TMA is a rare cause of TMA and has a...
Review Article
A snapshot of the cancer survivorship landscape in Singapore
Cancer remains the leading cause of morbidity in Singapore, and new cases have increased from 61,522 (2010–2014) to 91,574 (2019–2023), while the cancer death rate has fallen by 21% since 2012.1,2 The most common cancers affecting Singaporean men are...
Review Article
Guidelines on sexual health for women of reproductive age in Singapore
Sexual health is a fundamental component of overall health and well-being. The World Health Organization (WHO) defines sexual health as “a state of physical, emotional, mental, and social well-being related to sexuality; it is not merely the absence of...
Review Article
Lecanemab in Singapore: Appropriate use recommendations for early Alzheimer’s disease
Lecanemab is a recombinant humanised immunoglobulin gamma 1 monoclonal antibody (mAB), targeting -amyloid oligomers, protofibrils, and insoluble fibrils, facilitating their clearance, and thereby reducing amyloid plaques in the brain.1-4 In January 2023, the US Food and Drug Administration (FDA)...
Commentary
Acute medicine at the hospital front door: A Singapore health system priority
Hospital crowding is a visible and recurrent pressure in Singapore’s public hospitals. Although most apparent as emergency department congestion, it also reflects how patients move through the wider acute care system. For medically complex adults, the period after emergency...
Review Article
Diagnosis and management of haemophagocytic lymphohistiocytosis in adults: A narrative review and practical approach
Vignette:
A 55-year-old Chinese lady was admitted for pyrexia of unknown origin for 3 weeks, associated with a 5 kg weight loss. She had no rashes and no infective, autoimmune, or other systemic symptoms. On admission, she had fluid-refractory hypotension...
Original Article
Temporal trends of migraine and tension‑type headache in adolescents across China, Germany and the US
Adolescence is a pivotal period of neurodevelopment, hormonal fluctuation, and psychosocial transition, all of which converge to elevate vulnerability to migraine and tension-type headache (TTH).1,2 Recurrent headache in this age group disrupts school attendance, impairs peer relationships, and increases...
Original Article
Identifying adults with serious illness in Singapore’s surgical population and its impact on postoperative healthcare utilisation and costs
In developed and ageing populations globally, healthcare utilisation and expenditure are concentrated among a small proportion of individuals with complex healthcare needs.1 These “super-utilisers” comprise only approximately 5% of the population but account for a disproportionate share of healthcare...
Original Article
Exploring changes in recognition and stigmatisation towards individuals with schizophrenia in Singapore
Schizophrenia is a common yet debilitating illness that affects 1% of the global population and is associated with a reduction in life expectancy of about 15 years compared with the general population.1 With a typical onset in early adulthood,...
Original Article
Factors associated with willingness to quit smoking in a hospital-based smoking cessation programme
Cigarette smoking is a leading cause of preventable morbidity and mortality, and is a major contributor to premature death and cancer burden globally.1,2 Although the prevalence of smoking has declined since the 1970s, approximately 1 billion people continue to...
Call For Papers
Established in 1972, the Annals of the Academy of Medicine, Singapore is a monthly, open-access journal indexed in PubMed/MEDLINE, Science Citation Index Expanded, Scopus, and HINARI. We publish work that advances clinical practice, informs health policy, and improves population health, especially in the face of today’s growing chronic-disease burden and push for data-driven, patient-centred care.
Manuscript types
Original research, systematic reviews and meta-analyses, clinical guidelines and consensus statements, scoping reviews, health policy analyses, and evidence-based commentaries. We particularly welcome translational and implementation research with clear implications for Singapore and the Asia-Pacific region. Decisions and reviewer feedback will be communicated promptly.
