Annals Singapore - September 2026 issue cover, official journal of the Academy of Medicine, Singapore

Volume 55, Number 9 September 2026

Canagliflozin protects the diabetic kidney beyond glycemic control, with podocyte preservation linked to reduced proteinuria.

Illustration by Maria De-Castro

Beyond haemodynamics: Do SGLT2 inhibitors protect the podocyte?

Over the past decade, sodium-glucose cotransporter 2 (SGLT2) inhibitors have evolved from glucose-lowering agents into a cornerstone of kidney-protective therapy. Landmark trials, including CREDENCE,...

A randomised controlled study of canagliflozin in improving diabetic kidney disease through a podocyte protection mechanism

Diabetic kidney disease (DKD) is a common and severe microvascular complication of diabetes mellitus, a leading cause of chronic kidney disease (CKD), the primary...

Endoscopic combined intrarenal surgery versus conventional percutaneous nephrolithotomy for complex renal calculi: A retrospective study

Renal calculi are among the most prevalent urological diseases worldwide, severely impairing patients’ quality of life and increasing the healthcare burden. Epidemiological data from...

Coblation intracapsular tonsillectomy outcomes in paediatric obstructive sleep disordered breathing: A Singapore study

Obstructive sleep-disordered breathing (oSDB) in children, ranging from snoring to severe obstructive sleep apnoea (OSA), is associated with significant neurocognitive, behavioural, and cardiovascular sequelae.1...

Traditional Chinese Medicine in Singapore: Integrating education, practice, and research in a modern healthcare system

Introduction Complementary medicine refers to a non-mainstream therapeutic approach used alongside Western medicine (WM) to improve outcomes, with acupuncture alone and the full range of...
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