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Current Issue

Volume 52, Number 1
January 2023

A recent resurgence of paralytic poliomyelitis (polio) cases, from vaccine-derived poliovirus (VDPV) in non-endemic countries, highlights an increased risk of re-infection from the importation and transmission of wild poliovirus and VDPV.

This review provides an update on the clinical manifestations of polio and highlights key public health interventions aimed at reducing the risk of poliovirus transmission globally.

Illustration by Xinyu Li

Vaccination and surveillance: Two basic tools for a final poliomyelitis eradication

Over the past 3 decades, the Global Polio Eradication Initiative (GPEI) has strived to achieve a poliomyelitis (polio)-free world. Wild poliovirus (WPV) types 2...

Early COVID-19 booster is beneficial in cancer patients

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and its corresponding coronavirus disease (COVID-19) was first reported as a cluster of pneumonia cases in...

Catheter ablation as first-line treatment for paroxysmal atrial fibrillation

Pharmacotherapy has been the mainstay of atrial fibrillation (AF) treatment. As AF progresses from paroxysmal to persistent, electrical and structural remodelling of the atria...

Clinical efficacy and long-term immunogenicity of an early triple dose regimen of SARS-CoV-2 mRNA vaccination in cancer patients

The spread of the SARS-CoV-2 virus has led to the ongoing worldwide COVID-19 pandemic. Initial studies have reported an increased vulnerability of patients with...

Combating a resurgence of poliomyelitis through public health surveillance and vaccination

Singapore was certified poliomyelitis (polio)-free by the World Health Organization (WHO) on 29 October 2000, together with 36 other countries in the Western Pacific...


Review on Epidemic of Obesity

Rationale for Redefining Obesity in Asians


Board of Reviewers 2022

Association between self-care and chronic kidney disease in patients with type...

Surgical margins assessment reduces re-excision rates in breast-conserving surgery

Clinical outcome of bacterial endogenous endophthalmitis in 15 patients

Case studies of fetal mosaicisms detected by non-invasive prenatal testing