A recent resurgence of paralytic poliomyelitis (polio) cases, from vaccine-derived poliovirus (VDPV) in non-endemic countries, highlights an increased risk of re-infection from the importation and transmission of wild poliovirus and VDPV.

This review provides an update on the clinical manifestations of polio and highlights key public health interventions aimed at reducing the risk of poliovirus transmission globally.

^{Illustration by Xinyu Li}