ABSTRACT
Introduction: This is the second case of persistent acantholytic dermatosis in a patient with chronic renal failure, seen at the same institution in 2 years.
Clinical Picture: A 70-year-old Chinese man with end-stage renal failure on continuous ambulatory peritoneal dialysis for 6 months presented with pruritic rashes over the scalp and chest for 3 months. Histologically, the lesions resembled Darier’s disease. Differential diagnoses include Darier’s disease, Grover’s disease and perforating dermatosis in chronic renal failure. Treatment: The patient was treated with anti-histamines, topical steroids and emollients. Outcome: Resolution of pruritus was documented. However, the extensive hyperkeratotic papules remained persistent. Conclusion: A chronic non-remitting course is to be expected for this dermatoses in which the aetiology is unknown.A 70-year-old Chinese man with end-stage renal failure (ESRF), who has been on continuous ambulatory peritoneal dialysis for 6 months, was referred by the renal physician for pruritic rashes over the scalp and chest. The rashes were first noted about 3 months ago.
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