• Vol. 39 No. 10, 812–814
  • 15 October 2010

ANCA-negative Pauci-immune Crescentic Glomerulonephritis with Thrombotic Microangiopathy

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Pauci-immune crescentic glomerulonephritis (Pauci-immune CGN) is the most common cause of CGN. Thrombotic microangiopathy (TMA) defines a clinicopathological syndrome consisting of intraluminal platelet thrombosis in the microvasculature and the presence of fragmented red blood cells and thrombocytopaenia in the peripheral blood, and may be seen in haemolytic uraemic syndrome (HUS), thrombotic thrombocytopaenic purpura (TTP) and other conditions.

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