Antimicrobial drug resistance is recognized as a global problem; as such, The World Health Organization dedicated World Health Day on April 7 2011 to highlight this pressing issue. It is widely accepted that there is a direct correlation between antibiotic use and the development of antimicrobial resistance. Sadly, the pace of bacterial antimicrobial resistance development worldwide has surpassed the rate of newer antibiotic discovery to replace those rendered ineffective by resistance. Antimicrobial resistance is relevant to Singapore. In a surveillance study at 4 restructured hospitals in Singapore spanning 2006 to 2008, the prevalence of resistant Gram negative bacteria was high and the prescription volume of broad spectrum antibiotics was correspondingly high. When studies also report that 25% to 68% of hospital antibiotic prescribing had been suboptimal, we as members of the medical community need to sit up and do better.
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