This month’s issue of AAMS features various aspects of technology in Biomedical Engineering in the treatment of diseases and restoration of new organs. This article aims to highlight the burden of end-stage organ failure caused by their increasing prevalence, and cost of treatment. Currently, transplantation is the standard treatment for end-stage organ failure. However, considering the burden of disease, its socioeconomic sequelae and limits of the current treatment, there should be a less traumatic alternative treatment in addition to transplantation. Stem cell therapy combined with bioengineering techniques is the emerging treatment modality aimed at supporting, restoring or replacing failing organs.
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