Psoriasis is a common chronic inflammatory skin disease. On the other hand, autoimmune bullous diseases (AIBD) are less prevalent. Several case reports and studies have documented AIBD in patients with psoriasis.1,2 However, their causative factors are unclear. It has been hypothesised that certain antipsoriatic treatments such as ultraviolet irradiation, psoralen and coal tar could have triggered off the development of autoantibodies that cause AIBD.3 Treatment of AIBD in patients with psoriasis is challenging since systemic corticosteroids may potentially cause flares of pustular psoriasis. We report our experience in the management of psoriasis patients with AIBD in the National Skin Centre, a tertiary dermatology institution, in Singapore.
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