ABSTRACT
Introduction: Clinical pharmacology refers to the study of the safety, pharmacodynamic activity, mechanism of action, pharmacokinetics, metabolism and excretion of a drug in man.
Methods: Selected review of topics that provide guidance on practical issues for researchers conducting non-therapeutic investigational research in humans. Results: Close attention to the issues highlighted is needed to ensure successful research in this area of drug development. Resources dedicated to the discipline can logically optimise efficiency and outcome. Conclusions: There is increasing opportunity for clinical pharmacological research, offering an interesting career option to young physicians.Clinical pharmacology (CP) as a discipline comes in many guises. The perception for a medical student, and for many doctors, may be that of a painful series of lists of drugs to learn, the drugs being traditionally classified by functionality and effects.
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