Diabetes mellitus is a growing problem in Singapore, with a reported incidence of 11.3% of the Singapore population, a significant increase from 8.2% in 2004. With the implementation of a multidisciplinary approach combined with a clinical pathway, our major amputation rate (below- and above-knee amputation) has been reduced from 31.15% in 2002 to 11.01% in 2007. Nather et al in 2008 identified predictive factors leading to limb loss in diabetic patients to be peripheral vascular disease and infection.
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