Optimal antibiotic regimen is unknown for severe community-acquired pneumonia (SCAP) which has mortality rates of up to 67% locally.1 Recommended empiric regimens from the West cannot be extrapolated to our region where melioidosis is endemic2 and Streptococcus pneumoniae penicillin resistance is common.3 Unfortunately, studies that compare optimal antibiotic regimens for SCAP in Southeast Asia are lacking.
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