Optimal antibiotic regimen is unknown for severe
community-acquired pneumonia (SCAP) which has mortality
rates of up to 67% locally.1 Recommended empiric regimens
from the West cannot be extrapolated to our region where
melioidosis is endemic2 and Streptococcus pneumoniae
penicillin resistance is common.3 Unfortunately, studies that
compare optimal antibiotic regimens for SCAP in Southeast
Asia are lacking.
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