• Vol. 29 No. 1, 108–109
  • 15 January 2000

Endobronchial Mass in a Patient with Burkholderia pseudomallei Infection



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Introduction: Burkholderia pseudomallei infection, the great mimicker of infectious diseases, has protean clinical manifestations.

Clinical Picture: A 37-year-old man who presented with community-acquired pneumonia affecting the right upper lobe had unremitting fever. Bronchoscopy showed an endobronchial mass in the right upper lobe bronchus.

Treatment: Intravenous ceftriaxone and oral erythromycin, with empiric antituberculous treatment added later. This was subsequently switched to intravenous ceftazidime and oral doxycycline after the diagnosis was made.

Outcome: There was resolution of the endobronchial mass.

Conclusion: This case illustrates a unique and unreported presentation of melioidosis.

The diagnosis of Burkholderia pseudomallei infection is based on culture of clinical specimens such as blood or other body fluids, or serology using indirect haemagglutination (IHA) test and various antigen detection tests. Gram stain shows a bipolar “safety-pin” pattern or small gram-negative rods.

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