Extensive neutrophilic activation and infiltration occur in a number of dermatological conditions, resulting in typical features of pyrexia, neutrophilia, and raised erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). These conditions are namely generalised pustular psoriasis, acute generalised exanthematous pustulosis (AGEP) and Sweet syndrome, and they are termed as neutrophilic dermatoses with systemic manifestations.
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