• Vol. 32 No. 3, 408–410
  • 15 May 2003

Gyrate Atrophy of the Choroid: Two Cases

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ABSTRACT

Introduction: Gyrate atrophy of the choroid (GA) is a rare, inherited choroidal dystrophy that results in progressive deterioration in peripheral and night vision. This is the first documentation of GA in Singapore.

Clinical Picture: This report illustrates 2 cases of a sibling pair from a consanguineous union, presenting with the classical clinical features and biochemical abnormality of this condition.

Treatment and Outcome: One patient was treated with pyridoxine replacement and a low protein diet. However, his condition failed to improve. The other patient was left untreated.

Conclusion: Treatment was ineffective for the first patient. As yet, there is no proven treatment of GA.


Gyrate atrophy of the choroid (GA) is a rare choroidal dystrophy. It is an autosomal recessive disorder that results in progressive deterioration in peripheral and night vision.

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