Imaging-guided percutaneous bone biopsy can be rapidly performed under local anaesthesia with little patient discomfort. It has a useful role in the diagnosis and management of patients with bone lesions. The indications, contraindications, general principles, technique and possible complications of bone biopsy, performed using computed tomography guidance, are highlighted in this update.
Biopsy may be performed at surgery (open biopsy) or percutaneously (closed biopsy). Percutaneous bone biopsies are usually performed under imaging guidance using a variety of modalities, such as fluoroscopy1 and computed tomography (CT), and less commonly, ultrasonography (US) and magnetic resonance (MR) imaging.
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