Singapore has identified the biomedical sector as a key engine of economic growth and has invested heavily in promoting biomedical research. The Agency for Science Technology and Research (A*Star), in implementing this strategy, has provided state-of-the-art facilities, attracted, and developed talents and generously supported deserving research projects. Substantial progress...

New approaches in obstetric management of preterm births as well as the increased availability of tertiary neonatal care have resulted in improved survival rates of very low birthweight infants. The decline in mortality of these high-risk infants has been accompanied by an increase in the absolute number of infants...

Status epilepticus (SE) describes a clinical condition characterised by an epileptic seizure or a series of seizures that lasts for at least 30 minutes without consciousness being regained.1 Some authors have added a time line of 60 minutes. The incidence of generalised convulsive status epilepticus (GCSE) is between 40...

Major differences at clinicopathologic and molecular genetic levels are known to exist between the commonest variety of endometrial carcinoma, endometrioid adenocarcinoma (EC) and uterine papillary serous carcinoma (UPSC). The p53 tumour suppressor gene is expressed in the majority of cases of UPSC, in contrast to the usual situation in...

Streptococcus pneumoniae infection is the most common cause of community-acquired pneumonia worldwide.1 It has been associated with an approximately 10% rate of bacteraemia.2-4 Despite the advances in antibiotics, pneumococcal bacteraemia still carries a significant mortality rate.2-6 This article is available only as a PDF. Please click on "Download PDF" to...