Volume 40, Number 8

August 2011

Pharmacogenetics for Oncology Practice

Pharmacogenetics (PG) refers to the hereditary basis of drug response and has held the promise of pharmacotherapy that is individualised both in the selection...

Germline Genetic Testing to Predict Drug Response and Toxicity in Oncology— Reality or Fiction?

There is an increasing interest in personalised medicine, perhaps none greater than in the field of oncology. The idea of making therapeutic decisions based...

Inter-Ethnic Differences—How Important is it in Cancer Treatment?

Inter-individual differences in drug responses are well recognised and may be due to genetic or environmental differences. These genetic or environmental influences may also...

Tumour Genetics and Genomics to Personalise Cancer Treatment

The goal of any medical therapy is to accurately deliver the right drug against the right disease in the right patient. We have taken...

Challenges and Pitfalls in the Introduction of Pharmacogenetics for Cancer

Pharmacogenetics, by definition, refers to the study of genetic differences in metabolic pathways which can affect an individual’s responses to drugs in terms of...