The advent of recombinant growth hormone 20 years ago, which led to increased, albeit expensive, supplies of growth hormone (GH) in the market, has resulted in new treatments for short children. Apart from the 3 traditional indications to improve stature, namely (1) children with growth hormone deficiency, (2) Turner...

I am deeply conscious of the conspicuous honour of being invited to deliver the inaugural Centennial Lecture. This lecture has been specially established to commemorate the 100th anniversary of the founding of our Faculty of Medicine and of the National University of Singapore (NUS); it is the opening event...

Over the last 200 years, Western medicine has gradually spread across the globe, and has either been replaced or become integrated with traditional systems of medical care. Much of this expansion occurred during the colonial times. For example, Western medicine was introduced to Singapore by Thomas Prendergast, a surgeon...

The clinical behaviour of phyllodes tumours (PTs) of the breast is difficult to predict.1-5 While histological features have been traditionally used as predictors of clinical outcome, specific parameters that define recurrent likelihood are still not universally agreed upon.2 Though grade,6,7 stromal overgrowth,8,9 tumour necrosis and heterologous stromal elements,10 or...

Postgraduate medical education in Singapore may be regarded as having begun in 1910, when the first batch of doctors graduated from the Straits and Federated Malay States Government Medical School. This lecture reviews its development through 5 periods. This article is available only as a PDF. Please click on "Download...