Volume 43, Number 2

February 2014

Understanding Intra-tumour Heterogeneity—The Next Holy Grail of Cancer Therapeutics?

Advances in strategies to characterise tumours in the last decade have uncovered distinct molecular subtypes with prognostic and predictive relevance in both solid tumours and haematological malignancies. While conventional chemotherapy remains the mainstay in cancer therapeutics, the recognition of distinct “actionable genotypes” has led to a new paradigm shift...

The Use of Traditional Chinese Medicine Among Breast Cancer Patients: Implications for The Clinician

Complementary and alternative medicine practices and products are often believed to be holistic and natural cures for many aliments. Traditional Chinese medicine (TCM) is one of the most commonly used forms of complementary medicine in our culture. Rather than treating just the disease condition alone, TCM philosophy strives to...

Young Breast Cancer in a Specialised Breast Unit in Singapore: Clinical, Radiological and Pathological Factors

Breast cancer is the most common cancer to afflict women in Singapore, accounting for almost 30% of all female cancers. The greatest incidence occurred in women aged between 45 and 49 years but has more recently showed a shift towards older women in their late 50’s. There was also...

Singapore Rhabdomyosarcoma (RMS) Experience: Shall We Change Our Practice?

Rhabdomyosarcoma (RMS) constitutes nearly 4% of all children diagnosed with cancer in the ethnically diverse small island city of Singapore. It is the most common primary soft tissue malignancy of childhood and one which is highly sensitive to chemotherapy and radiation therapy leading to excellent overall survivals. In KK...

Epidemiology of Oral Cancer Diagnosed at a Singapore Tertiary Healthcare Institution

Oral and pharyngeal cancers grouped together are the sixth most common cancer seen worldwide. The annual estimated incidence is around 275,000 and 130,300 new cases of oral and pharyngeal cancers respectively. This article is available only as a PDF. Please click on “Download PDF” on top to view the full...