Advances in molecular techniques and technology have unravelled many of the secrets of diseases caused by single gene defects. In particular, the race to complete the sequencing of the human genome has exponentially accelerated the rate at which disease causing genes are being identified. This article is available only as...

The excitement surrounding the Human Genome Project and its impending completion has raised expectations of the possibilities for genetics in common disease. It is assumed that the identification of mutations that confer susceptibility will provide the basis for new means of detection, prevention and treatment. This article is available only...

Epilepsies are one of the most common neurological disorders, affecting about 3% of individuals at least once in a lifetime. It thus represents a major health care problem. Socio-economical and educational issues are well known. This article is available only as a PDF. Please click on “Download PDF” on top...

Myopia affects up to 70% of adults in Singapore, Taiwan, Hong Kong and Japan. The prevalence rates in these Asian countries are higher than those among Caucasians and Blacks in the United States and Europe. This article is available only as a PDF. Please click on “Download PDF” on top...

The World Health Organization has declared that the recent resurgence of tuberculosis (TB) is a global emergency. Southeast Asia, which is seeing the greatest increase in new TB patients, is at the epicentre of this pandemic. This article is available only as a PDF. Please click on “Download PDF” on...