One of the authors (KS) had finished his daily ward round with the multidisciplinary team in an acute inpatient ward a few moments earlier, before mulling over the contents of the present May issue of the AAMS. The care team just had a family session with the parents of...

Hallucinations are a hallmark symptom of schizophrenia and are commonly observed in other psychotic disorders. Auditory hallucinations (AH) are the most common subtype based on The International Pilot Study on Schizophrenia,1 but the occurrence of non-AH in psychotic patients has been less well characterised. Reported rates of visual...

Schizophrenia is a potentially devastating illness with a tremendous impact on the lives of both patients as well as the caregivers. Conceptualised as a lifelong disorder,1 the specific effects of schizophrenia on the brain and cognition are still being actively studied using modern imaging techniques such as magnetic resonance...

The brain is, weight for weight, the most metabolically active tissue in the body and generates a high load of reactive oxygen moieties. This burden is increased by a number of factors, including the oxidative potential of monoamines such as dopamine and excitatory neurotransmitters such as glutamate, as well...

The architecture of the neurobiology of schizophrenia is complex: it comprises an inherited vulnerability with multiple genes involved, and its interaction with a number of environmental factors. That the onset of psychosis typically occurs during late adolescence and early adulthood is suggestive that additional factors play significant roles along...