• Vol. 39 No. 11, 868–869
  • 15 November 2010

Management of a Patient with Schizophrenia and Underlying Pituitary Macroadenoma



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Hyperprolactinemia was found to be prevalent in a multi-centred study of 402 patients with schizophrenia, schizoaffective disorder and schizophreniform disorder treated with conventional antipsychotics and Risperidone. Antipsychotics inhibit the dopamine receptors and induce hyperprolactinemia via the tubulo-infundibular pathway, with subsequent downstream effects on multiple systems.

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