• Vol. 39 No. 12, 927–933
  • 15 December 2010

Management of Acute ST-Elevation Myocardial Infarction: Reperfusion Options



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Primary percutaneous coronary intervention and thrombolysis remain therapies of choice for patients presenting with ST-segment elevation myocardial infarction (STEMI). Clinical outcome in the management of acute STEMI is dependent on myocardial reperfusion time and reperfusion strategies. Optimisation of these strategies should take into consideration logistical limitations of the local medical systems and the various patient profiles. We review the reperfusion strategies and its history in Singapore, comparing its clinical application with that in some developed Western countries.

Cardiovascular disease is a leading cause of death globally. More than 920,000 myocardial infarctions (MI) are diagnosed annually in the United States. Of these, about 500,000 ST-elevation myocardial infarctions (STEMI) are estimated to occur each year.

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