New Treatments for Atopic Dermatitis – Facts, Comparisons and Uncertainties

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    Atopic dermatitis is associated with asthma and allergic rhinitis, and presents with a typical morphology and distribution. Eighty-four per cent of cases of atopic dermatitis are mild, 14% moderate, and 2% severe.1 There are 10 randomised controlled trials, and 1 systematic review addressing the appropriate frequency of application of topical corticosteroids for atopic eczema.2 In none of the studies was more frequent application superior to oncedaily application. However, the point estimates suggest that a small difference in favour of more frequent application cannot be excluded. As there is insufficient evidence for twice daily versus daily application, topical corticosteroids should be prescribed once or twice daily, using the lowest appropriate potency and acquisition cost

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