Multiple myeloma (MM) presenting as nodular liver masses is rare in clinical practice and the literature published thus far has been limited to few reports and case series. In a retrospective review of more than 2000 patients, Talamo et al reported that only 9 cases where there was nodular involvement of the liver by MM, whereas in one autopsy study, nodular liver involvement was present in 13.4% of patients. This discrepancy in fi ndings between clinical diagnosis and autopsy findings suggests that nodular involvement of the liver by MM may be under-diagnosed.
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