• Vol. 48 No. 8
  • 15 August 2019

Occam’s Razor or Hickam’s Dictum: A Case of Myopathy Double Trouble

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Dear Editor,

In clinical practice, Occam’s Razor is a principle that can
usually be applied to diagnose patients with rare neuromuscular
conditions. However, a second aetiology needs
to be considered if a single cause cannot account for all the
symptoms seen in patients. We report the rare case of a patient
who developed acute progressive generalised myopathy
associated with fever and eosinophilia shortly after returning
from a tropical island endemic for muscular sarcocystosis.
Subsequently, she was diagnosed with possible coexistent
renal cell carcinoma (RCC)-associated antinuclear matrix
protein 2 (antiNXP2) myositis with muscular sarcocystosis.
She was successfully treated with immunomodulatory
treatment, tumour resection and antiparasitic treatment.
She made a full and complete clinical recovery.

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