Penile cancer is a condition that accounts for approximately 0.4% of cancers among Singapore males. Overall, this is an uncommon cancer with higher rates in developing countries (2.8–6.8 per 100,000) compared to Western countries (as low as 0.3 per 100,000). However, in the UK, which is a developed country, there was a recent report of an increase in incidence rates from 1.10 to 1.33 per 100,000. This was attributed to the greater exposure to sexually transmitted oncogenic human papilloma viruses, which are associated with up to 40% of penile cancer cases. The most common site for penile cancer is the glans (48%), followed by prepuce (21%), glans and prepuce (9%), coronal sulcus (6%) and the shaft (<2%).
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