Pralatrexate Induces Long-Term Remission in Relapsed Subcutaneous Panniculitis-Like T-Cell Lymphoma



    Download PDF

    In subcutaneous panniculitis-like T-cell lymphoma (SPTL), infiltration of subcutaneous tissue by pleomorphic T-cells and benign macrophages is seen in skin nodules that mimic lobular panniculitis. SPTL affects young patients and about 20% develop haemophagocytic syndrome (HPS) which worsens survival significantly.1,2 We describe a case of aggressive SPTL in a patient with HPS who relapsed after multiple lines of therapy, but achieved complete and durable remission after extended pralatrexate therapy.

    This article is available only as a PDF. Please click on “Download PDF” on top to view the full article.