• Vol. 38 No. 5, 457–460
  • 15 April 2009

Prevalence of Chlamydia trachomatis in Singaporean Women Undergoing Termination of Pregnancy

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ABSTRACT

Introduction: The primary objective is to determine the prevalence of Chlamydia trachomatis infection among 200 women seeking termination of pregnancy (TOP) at National University Hospital (NUH), Singapore. The secondary objective is to determine the existence of high-risk sexual behaviours/practices among these women. Materials and Methods: Two endocervical swabs were taken from these women; one was transported in Chlamydia transport medium at 2ºC to 8 ºC, while the other was transported in a dry swab at room temperature and analysed with ligase chain reaction/enzyme immunoassay. Demographic data was collected with regard to relevant risk factors in a standard questionnaire. Results: 8% (16/200) of the women were found to be positive for Chlamydia trachomatis infection. Both the wet and dry methods of transport were equally effective in detection. 16.2% of the women in <25 years old group were positive versus 3.1% in the >25 years old group (P <0.001). 75% of the Chlamydia positive women had no symptoms/signs of Sexually Transmitted Infection (STI) or Pelvic Inflammatory Disease (PID). Of the 16 positive women, 14 (87.5%) did not use any contraception. All 12 women below 25 years of age did not use any contraception. Conclusion: Prevalence of infertility causing Chlamydia trachomatis infection in women is related to age. Thus the recommendation is the opportunistic screening of sexually active women less than 25 years of age.


Chlamydia trachomatis is the most common bacterially sexually transmitted infection (STI) in England and Wales.1 This infection if untreated can lead to pelvic inflammatory disease (PID), infertility and ectopic pregnancy.2 In fact pelvic inflammatory disease after a termination of pregnancy (TOP) is a well recognised complication and Chlamydia trachomatis is a commonly implicated pathogen in such cases.

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