• Vol. 41 No. 6, 268–270
  • 15 June 2012

Primary Intraventricular Lymphoma with Diffuse Leptomeningeal Spread at Presentation



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Primary central nervous system lymphoma (PCNSL) is a rare tumour accounting for 4% of all brain neoplasms. In immunocompetent patients, it tends to present as a large solitary hemispheric mass with periventricular lesions giving rise to ependymal seeding in 38% of the cases. Leptomeningeal metastases of the PCNSL at presentation are rare, accounting for only 2.3% of the cases. We present a rare case of primary intraventricular PCNSL with diffuse leptomeningeal spread at presentation. In this case study, we discuss the differential diagnoses and diagnostic approach to disseminated intraventricular masses.

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