• Vol. 29 No. 5, 563–564
  • 15 September 2000

Randomisation: Magical Cure for Bias?



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There is general consensus that randomised clinical trial (RCT) can provide the most valid conclusions about effects of different treatment as eligible patients are randomly allocated into two or more alternative treatments. Trials using non-randomised comparison groups like historical controls tend to yield more optimistic results than randomised trials.

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