• Vol. 43 No. 2, 125–126
  • 15 February 2014

Successful Management of Acute Mesenteric Ischaemia in a Pregnant Woman with Protein S Deficiency



Download PDF

Protein S is an endogenous anticoagulant that functions as a cofactor to activated protein C in the cleavage of clotting factors Va and VIIIa. Protein S deficiency, both hereditary and acquired forms, is a rare clinical condition, which usually manifests clinically as venous thromboembolism. Adverse pregnancy outcomes associated with protein S deficiency include recurrent fetal loss, intra-uterine growth retardation (IUGR) and intra-uterine death. Acute mesenteric venous thrombosis is one of the rare manifestations of isolated protein S deficiency. We report a pregnant patient with hereditary protein S deficiency who presented with an acute abdomen, later diagnosed as acute mesenteric ischaemia secondary to acute mesenteric venous thrombosis.

This article is available only as a PDF. Please click on “Download PDF” on top to view the full article.