• Vol. 42 No. 5, 253–256
  • 15 May 2013

Use of Propanolol for Treatment of Large Infantile Haemangiomas—A Report of Two Cases and Review of the Literature



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Infantile haemangioma (IH) is the most common, benign vascular tumour of infancy. Typically, IH goes through a proliferative phase in infancy, followed by involution over
several years. Watchful waiting is the best management with the natural history of spontaneous involution. For more than 4 decades, systemic corticosteroids remained the
mainstay of treatment for large IHs; however, not only is the safety profile far from ideal, but the response to treatment is unpredictable and rebound growth does occur upon
cessation of treatment. Recent reports on the efficacy and safety of propranolol catapulted the use of this treatment of IH to the first-line status. We describe 2 cases of large IHs treated successfully with oral propranolol.

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