Giant condyloma acuminate (GCA) first described by Buschke, also known as Buschke-Löwenstein tumour (BLT), is a slow growing, semi malignant neoplasm of the external genitalia and perianal region that has a recurrence tendency. Inspite of its histologically benign appearance, BLT clinically behaves in a malignant fashion, destroying adjacent tissues, and is reported as an entity intermediate between an ordinary condyloma acuminatum and squamous-cell carcinoma (SCC). BLT is likely to be a step into a spectrum of diseases that include malignant degeneration. Verrucous carcinoma (VC) was first described as a distinct well-differentiated variety of SCC by Ackerman. VC tends to appear mainly in oropharynx, genitalia and soles, although it may occur anywhere on the skin. Thus, VC has been known by several different names in relation to the anatomical site of the lesion. Different treatment modalities were applied on those patients with VC.
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