• Vol. 48 No. 8
  • 15 August 2019

White Matter Disease in a Young Adult Presenting as Rapidly Progressive Parkinsonism



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A 36-year-old Chinese lady presented with bilateral
hand tremors and difficulty in performing simple tasks
such as typing and handling of utensils. She also reported
short-term memory loss over the last 3 months. On initial
examination, bradykinesia was observed in her upper limbs
which was slightly more pronounced on the left. This was
associated with postural and intention tremors as well as left
upper limb dystonia, posturing and apraxia. Brisk tendon
reflexes were also elicited. Her sensory and motor power
and coordination examinations were unremarkable. Her
gait and speech were normal.

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