• Vol. 47 No. 5
  • 15 May 2018

Yellow Fever – What It Means for Singapore

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ABSTRACT

Outcomes of bariatric surgery for super obese Asians are not well reported. We aimed to compare short-term outcomes of laparoscopic sleeve gastrectomy (LSG) in Asian patients with body mass index (BMI) <47.5 kg/m2 to those with BMI ≥47.5 kg/m2. Materials and Methods: A total of 272 patients from a Singapore university hospital who underwent LSG from 2008 to 2015 with a follow-up of at least 6 months were included in the study. Primary endpoint was weight loss at 1-year and 3-years. Morbid obesity (Group 1, G1) was defined as BMI <47.5 kg/m2 and super obesity (Group 2, G2) was defined as BMI ≥47.5 kg/m2. Results: There were 215 patients in G1 and 57 patients in G2 (mean preoperative weight: 107.3 kg and 146.8 kg; mean follow-up: 27.9 and 26.8 months, respectively). Mean total weight loss at 3-years of 41.9 kg for G2 was significantly higher (P = 0.003) than 27.2 kg for G1. Mean percentage excess weight loss (EWL) did not differ at 3-years. There was no difference in operating time, blood loss, length of stay, 30-day morbidity and readmission. There were no conversions and mortality in both groups. Remission of hypertension (P = 0.001) and dyslipidaemia (P = 0.038) were significantly associated with achieving EWL percentage (%EWL) >50 in G1. Conclusion: LSG is an equally safe and effective operation in Asians with BMI ≥47.5 kg/m2 when compared to patients with BMI <47.5 kg/m2 in achieving significant weight loss and improvement in comorbidities. Super obese lose more weight but have lower %EWL.


Yellow fever (YF) is an arthropod-borne viral haemorrhagic disease transmitted by Aedes aegypti and Hemagogus mosquitoes, belonging to the flavivirus family which includes dengue, Zika and West Nile virus. Infected persons may have symptoms that range from subclinical infection to multi-organ failure and death.

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