Volume 43, Number 9

September 2014

Could the Devastation From Ebola Occur in Asia?

Outbreaks originating from animal reservoirs continue to take the world by surprise. Whether it is a novel virus such as Middle East respiratory syndrome (MERS) or severe acute respiratory syndrome (SARS) or a novel epidemiologic course of a known virus such as influenza and Ebola, no two outbreaks are...

Predicative Genetic Testing for Alzheimer’s Disease

Alzheimer’s disease (AD) is one of the most common types of dementia worldwide and it is of tremendous concern to individuals and society at large. Current diagnostic criteria are based on the Diagnostic and Statistical Manual for Mental Disorders, 5th Edition (DSM-5), and they are coded as major neurocognitive...

A New Population-based Reference for Gestational Age-specific Size-at-birth of Singapore Infants

Size-at-birth (birth weight, length and head circumference) is a simple clinical measure that is of importance to both neonatologists and obstetricians. It is commonly used in clinical practice to assess neonatal health. Birth weight and length have been demonstrated to be strong determinants of perinatal morbidity and survival; they...

Can Preoperative Scoring Systems be Applied to Asian Hip Fracture Populations? Validation of the Nottingham Hip Fracture Score (NHFS) and Identification of Preoperative Risk Factors in Hip Fractures

Osteoporotic hip fractures are common and have significant consequences on mortality and functional capability which indirectly has familial, social and economic repercussions. The inpatient mortality rates approach 4% to 12%, while 1-year mortality is between 12% to 37%.2, Studies from Denmark, Italy, the United Kingdom (UK), and the United...

Stroke Literacy in Singapore: Data From a Survey of Public Housing Estate Residents

Stroke is a leading cause of adult disability worldwide and the second most common cause of disease burden for Singaporeans aged 65 years and older. Acute thrombolytic treatment with intravenous tissue plasminogen activator (rtPA) within 4.5 hours of stroke onset is proven to reduce poststroke disability. However its utilisation...