Despite advancements in medical technologies, the art of medicine based on a one-to-one doctor-patient relationship has remained largely unchanged. Hippocrates, the founder of medicine, said this in the 4th century BC, “Cure sometimes, treat often, comfort always”. Sir William Osler, father of modern medicine also said in the 19th...

Diabetes mellitus (DM) is a major risk factor for cardiovascular disease, and coronary artery disease is the leading cause of death among adult diabetics. In Singapore, the proportion of people affected by diabetes has increased from 8.2% in 2004 to 11.3% in 2010. This article is available only as a...

Minimally invasive hepatectomy (MIH) is well established and routinely done for benign and malignant hepatic lesions in suitable cases. The advancements in video systems, energy devices and stapling equipment  in recent years have also made it feasible and safe for malignant hepatic lesions. This article is available only as a...

Direct oral anticoagulants (DOACs) describe 2 classes of oral anticoagulants that target thrombin (oral direct thrombin inhibitors) (DTI) and factor Xa (anti-FXa), both of which have been rapidly changing the anticoagulation landscape. This article is available only as a PDF. Please click on “Download PDF” on top to view the full...

Haematopoietic stem cell transplantation (HSCT) is an established treatment for many malignant and nonmalignant childhood conditions. Because of regional differences in disease spectrum and donor availability, transplant approaches may vary. This article is available only as a PDF. Please click on “Download PDF” on top to view the full article.