Editorial
Strengthening HRQOL Assessment in Singapore: Updated Norms for EQ-5D-5L and EORTC QLQ-C30
Health-related quality of life (HRQOL) is increasingly used as an important indicator of health outcomes for measuring the impact of illness and treatment among...
Complexity in primary care: Beyond multimorbidity in Healthier SG
The global ageing population, particularly older adults with complex biopsychosocial needs, drives increased healthcare utilisation, burdening both the health system and wider society.1,2 Primary care physicians...
Adolescent self-harm and suicide attempts in the emergency department in Singapore
The youth mental health crisis has taken centre stage globally in recent years with increased reporting of young persons suffering from mental health problems...
Organ donation in the paediatric intensive care unit: Time for change?
Organ transplantation remains the definitive treatment option for improving the lives of patients with end-stage organ failure. To our knowledge, the first solid organ...
Interventional radiology placement of totally implantable venous access devices in oncology practice
In November 1929, Werner Forssmann, a German surgical resident, attempted the first documented central venous catheter with a 35 cm-long catheter via his left...
The promise and challenges of pharmacogenomics in psychiatry
Pharmacogenomics (PGx) is an expanding field within precision medicine that is poised to play a crucial role in optimising patient outcomes, particularly in the...
Intrapleural fibrinolytic therapy: How low can we get?
Pleural infection is a common medical problem with significant mortality and morbidity.1 Despite advances in antibiotic therapy, the incidence of pleural infection is increasing...
Evolving therapies for atopic dermatitis: Bridging guidelines and practice
Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin condition characterised by dysregulated type 2 immune responses, skin barrier dysfunction and intense pruritus (itching)....
Can a Bayesian approach clarify if corticosteroids are beneficial for severe community-acquired pneumonia?
Despite advances in the antimicrobial treatment of sepsis and organ support in the intensive care unit (ICU), community-acquired pneumonia (CAP) remains a leading cause...
Stemming the tide of chronic kidney disease: A focus on primary care prevention
The prevalence of chronic kidney disease (CKD) among Singapore residents aged 18 to 74 years rose significantly from 8.8% in 2019–2020 to 13.8% in...