Letter to the Editor

Screening of nasopharyngeal cancer in high-risk familial cohort: A practical approach using a screening...

Dear Editor, In Singapore, nasopharyngeal cancer (NPC) is among the top 3 cancers afflicting middle-aged males (30–49 years old).1 Unfortunately, patients with early-stage NPC are...

VOWELS: A communication framework for disclosing medical errors in medical oncology and palliative care

Dear Editor, Recognising the impact of medical errors on patients and the doctor-patient relationship has underscored the need for better communication.1,2 For the most part,...

Patient’s degree of adherence, challenges & preferences towards medicine taking (PACT) in Singapore

Dear Editor, Medication nonadherence is a prevalent public health problem that compromises patients’ health outcomes and increases healthcare expenditures.1 Studies in Singapore showed that 25.7%–38.9%...

HLA-B*5801 testing: Is it time to consider mandatory testing prior to prescribing allopurinol in...

Dear Editor, Stevens-Johnsons Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are severe, life- threatening mucocutaneous reactions that most commonly occur as drug-related reactions.1 In recent...

Validating two international warfarin pharmacogenetic dosing algorithms for estimating the maintenance dose for patients...

Dear Editor, Predicting optimal warfarin dosing is difficult due to complex pharmacodynamics and pharmacokinetics, narrow therapeutic index and susceptibility to many factors.1 Genetic variations of...

Challenges to smoking cessation in patients with substance use disorders

Dear Editor, Despite significant progress in tobacco control measures and stringent smoking policies, cigarette smoking remains one of the largest preventable causes of death and...

Hantavirus haemorrhagic fever and renal syndrome, caused by the Hantaan virus in Singapore: A...

Dear Editor, We outline a case of a 59-year-old Malaysian man of Indian origin with no known past medical history apart from diabetes mellitus and...

Oral antiviral utilisation among older adults with COVID-19 in primary care: A population-wide study...

Dear Editor, Studies have repeatedly demonstrated the real-world effectiveness of oral antivirals (OAVs) in preventing hospitalisation and death in patients with mild-to-moderate COVID-19 at high...

Redefining seropositive rheumatoid arthritis: Clinical implications of anti-carbamylated protein on remission, radiographic damage and...

Dear Editor, Rheumatoid arthritis (RA) is a chronic disabling disease where continued disease activity translates to irreversible articular damage. Seropositivity for rheumatoid factor (RF) and...

Development of immediate and chronic spontaneous urticaria following mRNA COVID-19 vaccination: Tolerability of revaccination...

Dear Editor, Coronavirus 2019 (COVID-19) vaccination remains one of the key public health measures against the SARS-CoV-2 infection, significantly reducing illness severity and mortality...
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