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Review Article

The Golden Hours in Paediatric Septic Shock—Current Updates and Recommendations

Sepsis in children is a global health issue. The Global Health Observatory estimates that 58% of deaths in children under 5 years old are...

Ceftaroline—An Anti-MRSA Cephalosporin and Its Implications for Singapore

Ceftaroline fosamil (TAK-599 or PPI-0903)—the prodrug of the active metabolite, ceftaroline—was launched in Singapore in March 2013 under the tradename Zinforo® by AstraZeneca. It...

Cognitive Aspect of Diagnostic Errors

It was an unusually busy ward round. The newly promoted registrar was keen to review the patients handed over to him. But there were...

Changing Landscape of Nursing Homes in Singapore: Challenges in the 21st Century

Nursing homes trace their evolution to American alms-houses in the 1930s where retired nurses welcomed the elderly and ill into their homes. In Singapore,...

Does pulmonary metastasectomy of colorectal metastases translate to better survival? A systematic review

Colorectal cancer (CRC) is the one of most common cancers worldwide. Metastatic disease occurs in approximately half of all CRC patients, in either synchronous...

A Practical Guide to Ordering and Interpreting Coagulation Tests for Patients on Direct Oral...

Direct oral anticoagulants (DOACs) describe 2 classes of oral anticoagulants that target thrombin (oral direct thrombin inhibitors) (DTI) and factor Xa (anti-FXa), both of...

Glycaemic, Blood Pressure and Low Density Lipoprotein Cholesterol Control in Adult Patients with Diabetes...

Diabetes mellitus (DM) is a burgeoning global health epidemic, with an estimated 422 million people living with DM in 2014. The prevalence of DM...

Psychological Profile of Patients with Psoriasis

Psoriasis is a chronic inflammatory skin condition that affects approximately 2% of the population worldwide. The association between psoriasis and psychiatric disease is well...

Identification and Measurement of Frailty: A Scoping Review of Published Research from Singapore

Around a decade ago, frailty was an emerging research area and a nascent concept in many clinical specialties. Today, its growing relevance in both...

Cancer Immunotherapy – The Target is Precisely on The Cancer and Also Not

The immune system is intricately designed with unerring sophistication to identify—and if necessary—destroy invading pathogens, classically by distinguishing “self” from “non-self” proteins. The immune...
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