Editorial
Mycobacterium abscessus treatment: From empiricism to mechanism
Singapore has reached an inflection point in mycobacterial disease epidemiology, where nontuberculous mycobacterial (NTM) lung infections now nearly surpass tuberculosis (TB) in both incidence...
The Combined Singapore-Malaysia Congress of Medicine
When Singapore and Malaysia became two separate nations in 1965, the medical institutions duly followed and became distinct entities. There would henceforth be a...
From fragmented nights to unified care: Consensus directions in obstructive sleep apnoea
Obstructive sleep apnoea (OSA) has long been recognised as a highly prevalent and underdiagnosed disorder across the Asia-Pacific region, including Singapore.1,2 In this issue...
The junior doctor experience in Singapore through a temporal prism
Junior doctor well-being has been a pressing topic for the national healthcare system in Singapore for several years,1 with myriad implications on mental health,...
Gazing into the crystal ball of mortality prediction in conservative kidney care
Since Clyde Shields became the first patient with kidney failure to undergo long-term haemodialysis in 1960, the advent of kidney replacement therapy (KRT) has...
Trastuzumab-deruxtecan in breast cancer treatment: Balancing the triad of efficacy, safety and accessibility
Trastuzumab deruxtecan (T-DXd), an anti-human epidermal growth receptor 2 (HER2) antibody-drug conjugate (ADC), has emerged as a transformative therapy for metastatic breast cancer (MBC),...
Obesity in Singapore
The term “obesity” implies an excess of adipose tissue (fat) and excess adiposity is a health risk.‘f2 All definitions of obesity are arbitrary because...
Caring for the sexually assaulted child: Follow-up matters
In 2024, the United Nations Children's Fund (UNICEF) reported that 1 in 8 women (370 million) experienced sexual assault before the age of 18...
Pulling teeth or pulling together? Time to improve antibiotic prescribing in dentistry
Antibiotic use in third molar (3M) surgeries is commonplace despite a growing body of evidence showing that routine prophylactic antibiotics offer little benefit in...
War and the Medical Profession
The relationship between the profession of arms and the profession of healing is a close one, dating from antiquity. Among the Greek heroes who...