Editorial
Breast cancer-related lymphedema (BCRL): Should we be doing more or less for the axilla?
Breast cancer mortality has declined steadily over the years with breast cancer screening, and improvement in diagnostic and therapeutic regimens. Despite cancer survivors living...
Direct oral anticoagulant: Looking beyond convenience
Since the 2010 Food and Drug Administration approval of Dabigatran as the first non-vitamin-K antagonist oral anticoagulants or direct oral anticoagulants (DOACs) as it...
Freezing hope: Balancing realism and optimism in elective egg freezing
The 2022 White Paper on Singapore Women’s Development, which aimed at a fair and inclusive society where both women and men can pursue their...
Anti-osteoporosis drugs and reduction of mortality in cancer patients
Osteoporosis and cancer share a complex relationship, with each condition influencing the progression and outcomes of the other.1 Multiple factors, such as chemo- and...
Enhancing the accuracy of polycystic ovary syndrome diagnosis
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder, experienced by 1 in 10 women of childbearing age. Its aetiology is multifactorial and...
Vascular surgeons and best medical therapy: Missed opportunities?
Multiple guidelines recommend the use of best medical therapy (BMT) as secondary prevention for patients with peripheral arterial disease (PAD) but prescription and adherence...
Improving management of AL amyloidosis
In this issue of the Annals, Tan et al. on behalf of Singapore Myeloma Study Group presented the consensus guidelines on light chain (AL)...
Paradigm shifts in haemophilia A therapy with emicizumab prophylaxis in Asia
Over the past decade, the development of emicizumab, the first-in-class factor VIII (FVIII)-mimetic monoclonal antibody bispecific to activated factor IX and factor X, has...
COVID-19: The virus, vaccine and paediatric heart
The coronavirus disease 2019 (COVID-19) pandemic has resulted in much morbidity and mortality around the world. The development of vaccines has cushioned the effect...
Thiazide diuretics in chronic kidney disease: Is there still a role?
“The young physician starts life with 20 drugs for each disease, and the old physician ends life with one drug for 20 diseases.” —...